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Leendert Porcelijn Selected Research

Transfusion-Related Acute Lung Injury

10/2023Complement activation drives Transfusion-related acute lung injury via macrophage trafficking and formation of NETs.
11/2020Update on the pathophysiology of transfusion-related acute lung injury.
10/2020Multicenter Study on Differential Human Neutrophil Antigen 2 Expression and Underlying Molecular Mechanisms.
10/2020Evaluation of Platelet Responses in Transfusion-Related Acute Lung Injury (TRALI).
1/2020Biological and structural characterization of murine TRALI antibody reveals increased Fc-mediated complement activation.
10/2019The Role of Complement in Transfusion-Related Acute Lung Injury.
8/2017Low levels of interleukin-10 in patients with transfusion-related acute lung injury.
1/2017T regulatory cells and dendritic cells protect against transfusion-related acute lung injury via IL-10.
11/2016Elevation of C-reactive protein levels in patients with transfusion-related acute lung injury.
4/2014Molecular typing of human platelet and neutrophil antigens (HPA and HNA).
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Leendert Porcelijn Research Topics

Disease

18Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
01/2023 - 02/2010
17Hemorrhage
01/2023 - 11/2005
16Transfusion-Related Acute Lung Injury
10/2023 - 01/2010
15Thrombocytopenia (Thrombopenia)
04/2024 - 02/2009
11Neonatal Alloimmune Thrombocytopenia
01/2023 - 11/2005
6Neutropenia
09/2023 - 03/2011
3Inflammation (Inflammations)
12/2023 - 11/2016
3Lung Injury
10/2020 - 01/2012
3Infections
01/2020 - 03/2011
2COVID-19
04/2024 - 12/2023
2Autoimmune Diseases (Autoimmune Disease)
01/2020 - 03/2014
1Bernard-Soulier Syndrome (Giant Platelet Syndrome)
04/2024
1Thrombasthenia (Glanzmann Thrombasthenia)
04/2024
1Thrombosis (Thrombus)
04/2024
1Congenital amegakaryocytic thrombocytopenia
12/2022
1Acute Lung Injury
10/2019
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
10/2019
1Disease Susceptibility (Diathesis)
01/2019
1Chills
10/2018
1Fever (Fevers)
10/2018
1Transfusion Reaction
04/2014
1Carcinoma (Carcinomatosis)
01/2013
1Sepsis (Septicemia)
10/2010

Drug/Important Bio-Agent (IBA)

23AntibodiesIBA
10/2023 - 01/2010
14Inosine Triphosphate (ITP)IBA
01/2023 - 03/2014
10AutoantibodiesIBA
12/2023 - 03/2015
10IsoantibodiesIBA
11/2022 - 01/2009
9AntigensIBA
01/2023 - 11/2005
9Human Platelet AntigensIBA
11/2022 - 01/2009
7Immunoglobulin G (IgG)IBA
01/2024 - 02/2009
5Intravenous Immunoglobulins (IVIG)FDA Link
01/2021 - 03/2015
3Complement System Proteins (Complement)IBA
10/2023 - 10/2019
3Glycoproteins (Glycoprotein)IBA
01/2022 - 03/2014
3LipidsIBA
10/2020 - 04/2011
2VaccinesIBA
04/2024 - 12/2023
2Thrombopoietin (c-mpl Ligand)IBA
01/2020 - 01/2020
2human ITGB3 protein (HPA-1a)IBA
01/2020 - 01/2009
2Polysaccharides (Glycans)IBA
01/2020 - 01/2020
2N- (4- azido- 3- iodophenethylamidoisobutyl)norepinephrineIBA
10/2018 - 03/2011
2Interleukin-10 (Interleukin 10)IBA
08/2017 - 01/2017
2C-Reactive ProteinIBA
11/2016 - 03/2015
1HLA Antigens (Human Leukocyte Antigens)IBA
04/2024
1Heparin (Liquaemin)FDA LinkGeneric
04/2024
1BNT162 VaccineIBA
12/2023
1Platelet Factor 4IBA
12/2023
1Messenger RNA (mRNA)IBA
12/2023
1ChAdOx1 nCoV-19IBA
12/2023
1Ad26COVS1IBA
12/2023
12019-nCoV Vaccine mRNA-1273IBA
12/2023
1COVID-19 VaccinesIBA
12/2023
1LipopolysaccharidesIBA
10/2023
1Thrombopoietin ReceptorsIBA
12/2022
1IndiumIBA
01/2022
1Proteins (Proteins, Gene)FDA Link
11/2020
1OsteopontinIBA
11/2020
1CeramidesIBA
10/2020
1Indicators and Reagents (Reagents)IBA
10/2020
1Rituximab (Mabthera)FDA Link
01/2020
1Monoclonal AntibodiesIBA
01/2020
1Platelet Membrane Glycoprotein IIbIBA
01/2020
1Immunoglobulin M (IgM)IBA
01/2020
1Anti-Bacterial Agents (Antibiotics)IBA
10/2018
1Granulocyte Colony-Stimulating Factor (G-CSF)IBA
10/2018
1Blood Group Antigens (Blood Groups)IBA
10/2018
1Acute-Phase Proteins (Acute-Phase Protein)IBA
11/2016
1IntegrinsIBA
11/2015
1Tetradecanoylphorbol AcetateIBA
03/2014
1Adenosine Diphosphate (ADP)IBA
03/2014
1Sunitinib (Sutent)FDA Link
01/2013

Therapy/Procedure

4Blood Transfusion (Blood Transfusions)
10/2019 - 10/2010
3Platelet Transfusion (Blood Platelet Transfusions)
04/2024 - 01/2014
3Therapeutics
10/2023 - 11/2005
1Cardiopulmonary Bypass (Heart-Lung Bypass)
04/2011
1Laparotomy
10/2010
1Liver Transplantation
02/2010